ELDERBERRY: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews (2024)

Overview

Elderberry (Sambucus nigra) is the dark purple berry from the European elder tree. It has a long history of use for cold and flu.

Elderberry is a popular ingredient in supplements. It might affect the immune system, and also seems to have activity against viruses, including the flu.

Elderberry is commonly used for the common cold, flu, high cholesterol, and many other conditions, but there is no good scientific evidence to support most of these uses, with the possible exception of the flu. There is also no good evidence to support using elderberry for COVID-19.

Don't confuse elderberry with American Elder, Elderflower, or Dwarf Elder. These aren't the same and have different effects.

Uses & Effectiveness ?

Possibly Effective for

  • Flu (influenza). Taking a specific elderberry extract syrup (Sambucol, Nature's Way) seems to reduce flu symptoms when taken within 48 hours of the first symptoms. But it might not be helpful in some people, including those with lung conditions or children under 12 years of age.

There is interest in using elderberry for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.

Side Effects

When taken by mouth: Elderberry is commonly consumed in foods. Elderberry extract is possibly safe when taken for up to 12 weeks. There isn't enough reliable information to know if it is safe to use for longer than 12 weeks.

It is possibly unsafe to consume elder leaves or stems, or unripe or uncooked elderberries. Cooked elderberry seems to be safe, but raw and unripe fruit might cause nausea, vomiting, or severe diarrhea.

Special Precautions and Warnings

When taken by mouth: Elderberry is commonly consumed in foods. Elderberry extract is possibly safe when taken for up to 12 weeks. There isn't enough reliable information to know if it is safe to use for longer than 12 weeks.

It is possibly unsafe to consume elder leaves or stems, or unripe or uncooked elderberries. Cooked elderberry seems to be safe, but raw and unripe fruit might cause nausea, vomiting, or severe diarrhea. Children: Elderberry extract is possibly safe in children 5 years of age or older when taken by mouth for up to 3 days. There isn't enough reliable information to know if it is safe for children younger than 5 years of age to take elderberry. Unripe or uncooked elderberries are possibly unsafe. Don't give them to children.

Pregnancy and breast-feeding: There isn't enough reliable information to know if elderberry extract is safe to use when pregnant or breast-feeding. Stay on the safe side and stick to food amounts.

"Autoimmune diseases" such as multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA), or other conditions: Elderberry might cause the immune system to become more active. This could increase the symptoms of autoimmune diseases. If you have one of these conditions, it's best to avoid using elderberry.

Interactions ?

    Moderate Interaction

    Be cautious with this combination

  • Medications that decrease the immune system (Immunosuppressants) interacts with ELDERBERRY

    Elderberry can increase the activity of the immune system. Some medications, such as those used after a transplant, decrease the activity of the immune system. Taking elderberry along with these medications might decrease the effects of these medications.

Dosing

Elderberry fruit extracts have most often been used by adults in doses up to 1200 mg by mouth daily for 2 weeks. Elderberry is available in many different types of products, including syrups and mouth rinses. Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition.

Don't consume green, unripe, uncooked elderberries. They contain toxins and can be poisonous.

Next

  • Common Searches:
  • Alpha Lipoic Acid
  • Apple Cider Vinegar
  • Black Cohosh
  • Calcium
  • Chromium
  • Coenzyme Q - 10
  • DHEA
  • Flaxseed
  • Folic Acid
  • Ginko
  • Glucosamine
  • Melatonin
  • Niacin
  • Magnesium
  • Probiotics
  • Red Yeast Rice
  • St. John's Wort
  • Vitamin C
  • Vitamin D
  • Vitamin E

Show More Show Less

You Might Also Like

Cold and Flu Symptoms Across the U.S.

Someone in Your House Sick? What to Do

Cold vs Flu: Does it Matter?

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circ*mstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.

ELDERBERRY: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews (2024)

FAQs

ELDERBERRY: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews? ›

It might affect the immune system, and also seems to have activity against viruses, including the flu. Elderberry is commonly used for the common cold, flu, high cholesterol, and many other conditions, but there is no good scientific evidence to support most of these uses, with the possible exception of the flu.

What medications should not be taken with elderberry? ›

Because elderberry may stimulate the immune system, it could interfere with medications taken to suppress the immune system. These medications include corticosteroids (prednisone) and medications used to treat autoimmune diseases. People with organ transplants should also avoid elderberry.

What are the negative side effects of elderberry? ›

The common side effects of taking raw elderberry plant products, such as fruit, flower, leaves, bark, or root include:
  • Stomach problems.
  • Nausea and vomiting.
  • Diarrhea and constipation.

Which autoimmune diseases should avoid elderberry? ›

People who have autoimmune conditions such as multiple sclerosis (MS), rheumatoid arthritis, lupus, psoriasis, and inflammatory bowel disease should not use elderberry. Elderberry may boost the immune system, which can worsen autoimmune diseases. Many autoimmune disorders require immunosuppressant drugs.

Who shouldn't take elderberry syrup? ›

Children and pregnant or breastfeeding women shouldn't eat elderberries at all, since it's not known how the berries might affect them. Elderberry supplements can interfere with diabetes medications, laxatives and diuretics, so you shouldn't take elderberry supplements if you are on any of these medications.

Why is elderberry not FDA approved? ›

Like elderberry, many other herbal cold remedies are not regulated by the FDA. The few studies conducted on these supplements are not shown to reduce the length of cough and cold symptoms. They also aren't shown to prevent colds or flu.

Can elderberry affect blood pressure? ›

Elderberries may be beneficial for the heart, as they have been associated with positive effects on blood pressure; the anthocyanin content increases the release of nitric oxide—which helps widen the blood vessels and improves blood flow, leading to a decrease in blood pressure.

When not to use elderberry? ›

"Autoimmune diseases" such as multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA), or other conditions: Elderberry might cause the immune system to become more active. This could increase the symptoms of autoimmune diseases.

Is it bad to take elderberry everyday? ›

Yes, you can! You can safely take elderberry daily as long as you follow the recommended dosage instructions. Elderberry is safe to take all year round.

Is elderberry safe for kidneys? ›

Cardiovascular disease risk biomarkers and liver and kidney function are not altered in postmenopausal women after ingesting an elderberry extract rich in anthocyanins for 12 weeks. J Nutr. 2009 Dec;139(12):2266-71. doi: 10.3945/jn.

What do doctors say about elderberry? ›

Opinions vary on whether elderberry is helpful, but most doctors believe it's safe to have in small doses. But unripe or uncooked berries or flowers from the plant can cause nausea, vomiting, and diarrhea. Larger amounts can cause even more serious poisoning.

Why can't people with MS take elderberry? ›

Some supplements (e.g., Echinacea, elderberry), when used regularly, may actually worsen MS by overstimulating the immune system. Some supplements may interfere with medications or medical conditions and may not be safe to use.

Does elderberry cause pancreatitis? ›

Some case reports of more severe adverse effects associated with elderberry, including acute pancreatitis, also exist. Unripe elderberries, as well as the stems and leaves of the elder tree, contain cyanide-producing compounds that can be toxic if ingested.

Does elderberry interact with any medications? ›

Elderberry has no known severe, serious, or moderate interactions with other drugs. Elderberry has mild interactions with at least 28 different drugs.

Can elderberry have side effects? ›

The elderberry plant contains a chemical that produces cyanide in the leaves or other plant parts and in the unripe green fruit. This can cause nausea, vomiting, and diarrhea, or more serious side effects if consumed in large quantities.

What is the toxin in elderberries? ›

The uncooked berries, leaves, twigs and seeds contain a cyanogenic compound. Ingestion may cause nausea, vomiting and diarrhea. Large amounts may cause lethargy, dizziness and drowsiness. Toxicity is not expected with ingestion of the cooked berries.

Does elderberry affect your kidneys? ›

Cardiovascular disease risk biomarkers and liver and kidney function are not altered in postmenopausal women after ingesting an elderberry extract rich in anthocyanins for 12 weeks.

Can you take Tylenol and elderberry together? ›

Interactions between your drugs

No interactions were found between elderberry and Tylenol. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Is elderberry bad for inflammation? ›

Results demonstrated that elderberries have high potential in reducing cellular oxidative stress as well as in preventing inflammatory processes. Thus, elderberries have high potential as health promoters, acting as functional foods or as sources of nutraceuticals.

Can you take magnesium and elderberry together? ›

No interactions were found between Elderberry Gummies with Vitamin C and Zinc and magnesium oxide.

References

Top Articles
Latest Posts
Article information

Author: Annamae Dooley

Last Updated:

Views: 5791

Rating: 4.4 / 5 (65 voted)

Reviews: 88% of readers found this page helpful

Author information

Name: Annamae Dooley

Birthday: 2001-07-26

Address: 9687 Tambra Meadow, Bradleyhaven, TN 53219

Phone: +9316045904039

Job: Future Coordinator

Hobby: Archery, Couponing, Poi, Kite flying, Knitting, Rappelling, Baseball

Introduction: My name is Annamae Dooley, I am a witty, quaint, lovely, clever, rich, sparkling, powerful person who loves writing and wants to share my knowledge and understanding with you.